教学科研

杨兴斌

发布日期:2017-10-23     作者:      分享到:


杨兴斌男,196910月生,汉族,陕西榆林市横山人,现为澳门威斯人7026com院长、教授、博士生导师。1997年获北京化工大学精细化工工学硕士学位,2004年获空军军医大学(原第四军医大学)医(药理)学博士学位。澳大利亚西澳大学University of Western Australia)访问教授。担任陕西省食品绿色加工与安全控制工程实验室主任,陕西省农产品贮藏加工危害因子风险评估实验室主任,西部果品资源高值利用教育部工程研究中心技术委员会副主任,陕西省食品科学与工程实验教学示范中心主任,教育部药用资源与天然药物化学重点实验室、西北濒危药材资源开发国家工程实验室学术带头人。目前,主要从事食品加工与安全检测、微生态营养与代谢、保健食品及特膳食品开发等研究工作。

1)基础理论研究:系统研究秦巴山区植源性功能糖与类黄酮的营养聚集化精深加工和营养调控分子机制,发展了功能糖与类黄酮的营养互作理论,提出食品营养物质基础整体观的“网络食品功能学”研究技术;研究功能糖基于肠菌群代谢产生的琥珀酸激活肠道糖异生进而发挥间接的体内血糖稳态调控机制,完善功能糖与肠菌群互作调节血糖稳态的营养理论与科学认知;发现长期被推测为致癌的限量摄入物硝酸盐、亚硝酸盐及富含硝酸盐的菠菜在维持血管内皮功能稳态中的重要营养价值;阐明含三甲胺结构的卵磷脂等甲基供体营养素经肠道生理菌群代谢产生氧化三甲胺(TMAO)进而诱发肝脂代谢危害,揭示肠道AKK菌与肝损伤的关系,提高卵磷脂等营养素的营养与安全“利与弊”的科学认知。

2)产品产业服务:参与驰名产品“白加黑”双层缓释片的研发工作(德国拜耳公司);先后为企业开发爽QQ牌水苏糖口香糖(企业标准Q/DSP 010-2007)、肠内美人牌水珍唯美食品、水苏冲剂(国食健字G20040234)和德施普粉(国食健字G20080008)等系列功能或保健食品(市场化商品),产生重要的经济与社会效益;研究猕猴桃的采后气体射流冲击干燥和冷冻干燥技术及理论,开发猕猴桃的休闲食品;开发马铃薯主食化馒头与面条食品及血糖生成指数( GI)馒头;探究功能糖与多酚的互作营养理论,开发益常顺牌茶多酚复合益生元速溶茶和固体饮料、速溶益生茯砖茶、大豆益生菌发酵国体饮料和酵素等肠道微生态功能食品产品;成功研制水槽升降式新一代豆芽机食品装备。熟悉保健食品的申报注册工作,具备丰富的生物制品产、学、研一体化与产业战略发展管理经验。

3)主要学术任职:担任Food & FunctionSCI一区)编辑顾问委员、Frontiers in PharmacologySCI二区)和Frontiers in NutritionSCIE评论编辑及编委,兼任《Journal of Food & Nutritional Disorders》和《Journal of Food Processing & Technology》杂志主编,以及《食品科学》、《食品安全质量检测学报》、《农产品加工》、《食品工业科技》、《陕西师范大学学报》、eFood等杂志编委。陕西省高校科协联合会理事、陕西省农业工程学会常务副理事长、陕西省食品科学技术学会副理事长、陕西省营养学会副理事长、中国校园团餐联盟专家委员、中国农学会食物与营养专业委员会常务委员、中国农产品开发服务协会农产品加工业分会委员,马铃薯主食开发技术协作组理事会副理事长,中国猕猴桃产业技术创新战略联盟理事,国家农产品加工营养大数据创新战略联盟副理事长。

4)专利与论著:先后获一种多功能复合速溶茶及其制备方法和用途,ZL201510381645.9”一种水槽升降式豆芽机,ZL201621060915.2”一种紫阳富硒绿茶含硒多糖及其制备方法和用途,ZL201110293739.2”一种协同降血脂的双层缓释片,ZL201110382887.1”授权专利10余项;参编《功能食品学》(科学出版社,201781日出版, 副主编)、《临床新药手册》(清华大学出版社,200612月出版,编委)等编著5部;参与制订速溶茶等行业标准4项;先后Antioxidants & Redox Signaling (IF 8.2), Trends in Analytical Chemistry (IF 8.4), American Journal of Clinical Nutrition (IF 6.5), Free Radical Biology & Medicine (IF 5.7), Molecular Nutrition and Food Research, Journal of Agricultural and Food Chemistry, Food & Function, Food ChemistrySCI杂志发表论文150余篇,论文被引3000余次,论文H指数为34

5)科技项目与获奖:先后主持国家自然科学基金面上项目4项及国家重大科技专项等项目10余项。先后获“天然多糖及寡糖的色谱质量控制技术构建与生物功能研究”、“食物类黄酮与功能糖的化学与分子营养的应用基础研究”、“功能糖与类黄酮的分子营养及互作机制研究”等陕西省科技进步一等奖1项、二等奖2项和陕西高等学校科学技术一等奖2项、二等奖1项;2018年获得第二届全国沙产业创新创业大赛“双创之星”荣誉称号。2011年获中国食品产业产学研创新发展杰出科研人才奖,2013年获陕西省职工优秀科技创新人物称号,2014年获省部级劳动模范、全国模范军队转业干部称号(中共中央组织部等四部委“国转联[2014]4号文件”联合授予)2014年入选陕西省中青年科技创新领军人才2019年入选陕西省创新人才推进计划(科技创新团队)。

近三年代表性SCI论文JCR大类分区,出版年或最新IF

  1. Qiu Wu, Xiangnan Zhang, Yan Zhao, Xingbin Yang*. High L-carnitine ingestion impairs liver function by disordering gut bacteria composition in mice. Journal of agricultural and food chemistry, 2020, DOI:10.1021/acs.jafc.9b08313 (SCI一区, IF 3.571)

  2. Jin Zhang, Yan Zhao*, Daoyuan Ren, Xingbin Yang*. Effect of okra fruit powder supplementation on metabolic syndrome and gut microbiota diversity in high fat diet-induced obese mice. Food Research International, 2020, 130, DOI: 10.1016/j.foodres.2019.108929 (SCI二区, IF 3.579)

  3. Aamina Alim, Ting Li*, Tanzeela Nisar, Daoyuan Ren, Yueyue Liu, Xingbin Yang*. Consumption of two whole kiwifruit (Actinide chinensis) per day improves lipid homeostasis, fatty acid metabolism and gut microbiota in healthy rats. International Journal of Biological Macromolecules, 2020, 156, 186-195 (SCI二区, IF 4.784)

  4. Xichuan Zhai, Dehui Lin*, Wenwen Li, Xingbin Yang*. Improved characterization of nanofibers from bacterial cellulose and its potential application in fresh-cut apples. International Journal of Biological Macromolecules, 2020, 149, 178-186 (SCI二区, IF 4.784)

  5. Zhe Liu, Dehui Lin*, Patricia Lopez-Sanchez, Xingbin Yang*. Characterizations of bacterial cellulose nanofibers reinforced edible films based on konjac glucomannan. International Journal of Biological Macromolecules, 2020, 145, 634-645 (SCI二区, IF 4.784)

  6. Zhong Zhang, Xin Ma, Bowei Li, Jia Zhao, Ji Qi, Guoying Hao, Rong Jianhui*, Xingbin Yang*. Fluorescence detection of 2,4-dichlorophenoxyacetic acid by ratiometric fluorescence imaging on paper-based microfluidic chips. Analyst, 2020, 145(3), 963-974 (SCI二区, IF 4.019)

  7. Chengcheng Yang, Yan Zhao*, Daoyuan Ren, Xingbin Yang*. Protective effect of saponins-enriched fraction of Gynostemma pentaphyllum against high choline-induced vascular endothelial dysfunction and hepatic damage in Mice. Biological & Pharmaceutical Bulletin, 2020, 43(3), 463-473 (SCI四区, IF 1.54)

  8. Yalong Lu, Aiqing Zhao*, Yingmei Wu, Yan Zhao, Xingbin Yang*. Soybean soluble polysaccharides enhance bioavailability of genistein and its prevention against obesity and metabolic syndrome of mice with chronic high fat consumption. Food & Function, 2019, 10(7), 4153-4165 (SCI一区, IF 3.241)

  9. Haiping Du, Qi Wang, Xingbin Yang*. Fu brick tea alleviates chronic kidney disease of rats with high fat diet consumption through attenuating insulin resistance in skeletal muscle. Journal of Agricultural and Food Chemistry, 2019, 67(10), 2839-2847 (SCI一区, IF 3.571)

  10. Shixi Song, Xingyu Wang*, Ke Xu, Guanmei Xia, Xingbin Yang*. Visualized detection of vibrio parahaemolyticus in food samples using dual-functional aptamers and cut-assisted rolling circle amplification. Journal of Agricultural and Food Chemistry, 2019, 67(4), 1244-1253 (SCI一区, IF 3.571)

  11. Xiangnan Zhang, Qiu Wu, Yan Zhao, Xingbin Yang*. Decaisnea insignis seed oil inhibits trimethylamine‑N‑oxide formation and remodels intestinal microbiota to alleviate liver dysfunction in L‑Carnitine feeding mice. Journal of Agricultural and Food Chemistry, 2019, 67(47), 13082-13092 (SCI一区, IF 3.571)

  12. Yueyue Liu, Ting Li*, Aamina Alim, Daoyuan Ren, Yan Zhao, Xingbin Yang*. Regulatory effects of stachyose on colonic and hepatic inflammation, gut microbiota dysbiosis, and peripheral CD4+ T cell distribution abnormality in high-fat diet-fed mice. Journal of Agricultural and Food Chemistry, 2019, 67(42), 11665-11674 (SCI一区, IF 3.571)

  13. Qiu Wu, Yan Zhao*, Xiangnan Zhang, Xingbin Yang*. A faster and simpler UPLC-MS/MS method for the simultaneous determination of trimethylamine N-oxide, trimethylamine and dimethylamine in different types of biological samples. Food & Function, 2019, 10(10), 6484-6491 (SCI一区, IF 3.241)

  14. Daoyuan Ren, Yan Zhao*, Quan Zheng, Aamina Alim, Xingbin Yang*. Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells. Food & Function, 2019, 10(4), 2186-2197 (SCI一区, IF 3.241)

  15. Aiqing Zhao, Bini Wang, Xiaohong Tian*, Xingbin Yang*. Combined soil and foliar ZnSO4 application improves wheat grain Zn concentration and Zn fractions in a calcareous soil. European Journal of Soil Science, 2019, 1-14 ( SCI二区, IF 2.818)

  16. Aamina Alim, Ting Li*, Tanzeela Nisar, Daoyuan Ren, Xichuan Zhai, Yaxing Pang, Xingbin Yang*. Antioxidant, antimicrobial, and antiproliferative activity-based comparative study of peel and flesh polyphenols from Actinidia chinensis. Food & Nutrition Research, 2019, 63, 1-10 (SCI二区, IF 2.553)

  17. Shixi Song, Xingyu Wang*, Ke Xu, Lufang Ning, Xingbin Yang*. Rapid identification and quantitation of the viable cells of Lactobacillus casei in fermented dairy products using an aptamer-based strategy powered by a novel cell-SELEX protocol. Journal of Dairy Science, 2019, 102(12), 10814-10824 (SCI二区, IF 3.082)

  18. Shixi Song, Xingyu Wang*, Ke Xu, Qiao Li, Lufang Ning, Xingbin Yang*. Selection of highly specific aptamers to Vibrio parahaemolyticus using cell-SELEX powered by functionalized graphene oxide and rolling circle amplification. Analytica Chimica Acta, 2019, 1052, 153-162 (SCI二区, IF 5.256)

  19. Zhong Zhang, Xin Ma, Mengfan Jia, Bowei Li, Jianhui Rong*, Xingbin Yang*. Deposition of CdTe quantum dots on microfluidic paper chips for rapid fluorescence detection of pesticide 2,4-D. Analyst, 2019, 144(4), 1282-1291 (SCI二区, IF 4.019)

  20. Lufang Ning, Xingyu Wang*, Ke Xu, Shixi Song, Qiao Li, Xingbin Yang*. A novel isothermal method using rolling circle reverse transcription for accurate amplification of small RNA sequences. Biochimie, 2019, 163, 137-141 (SCI三区, IF 3.362)

  21. Xiangnan Zhang, Qiu Wu, Yan Zhao, Alim Aimy, Xingbin Yang*. Consumption of post-fermented Jing-Wei Fuzhuan brick tea alleviates liver dysfunction and intestinal microbiota dysbiosis in high fructose diet-fed mice. Rsc Advances, 2019, 9(30), 17501-17513 (SCI三区, IF 3.049)

  22. Chen Liu, Zhong Zhang*, Qingjun Kong, Runguang Zhang, Xingbin Yang*. Enhancing the antitumor activity of tea polyphenols encapsulated in biodegradable nanogels by macromolecular self-assembly. Rsc Advances, 2019, 9(18), 10004-10016 (SCI三区, IF 3.049)

  23. Xinxin Jiang, Dehui Lin, Hongjun Shao, Xingbin Yang*. Antioxidant properties of Komagataeibacter hansenii CGMCC 3917 and its ameliorative effects on alcohol-induced liver injury in mice. CyTA-Journal of Food, 2019, 17(1), 355-364 (SCI四区, IF 1.605)

  24. Xichuan Zhai, Dehui Lin*, Yan Zhao, Xingbin Yang*. Bacterial cellulose relieves diphenoxylate-induced constipation in rats. Journal of Agricultural and Food Chemistry, 2018, 66, 4106-4117 (SCI一区, IF 3.412)

  25. Xichuan Zhai, Dehui Lin*, Yan Zhao, Wenwen Li, Xingbin Yang*. Enhanced anti-obesity effects of bacterial cellulose combined with konjac glucomannan in high-fat diet-fed C57BL/6J mice. Food & Function, 2018, 9, 5260–5272 (SCI一区, IF 3.289)

  26. Qiu Wu, Paul W. Needs*, Yalong Lu, Paul A. Kroon, Daoyuan Ren, Xingbin Yang*. Different antitumor effects of quercetin, quercetin-3’-sulfate and quercetin-3-glucuronide in human breast cancer MCF-7 cells. Food & Function, 2018, 9, 1736-1746 (SCI一区, IF 3.289)

  27. Qiu Wu, Paul A. Kroon, Hongjun Shao, Paul W. Needs*, Xingbin Yang*. Differential effects of quercetin and two of its derivatives, isorhamnetin and isorhamnetin-3-glucuronide, in inhibiting the proliferation of human breast-cancer MCF7 cells. Journal of Agricultural and Food Chemistry, 2018, 66, 7181-7189 (SCI一区, IF 3.412)

  28. Xichuan Zhai, Dehui Lin*, Dongjie Liu, Xingbin Yang*. Emulsions stabilized by nanofibers from bacterial cellulose: new potential food-grade Pickering emulsions. Food Research International, 2018, 103, 12-20 (SCI二区, IF 3.520)

  29. Yalong Lu, Wenfeng Li*, Xingbin Yang*. Soybean soluble polysaccharide enhances absorption of soybean genistein in mice. Food Research International, 2018, 103, 273-279 (SCI二区, IF 3.520)

  30. Yingmei Wu, Wenfeng Li, Yalong Lu, Qiu Wu, Xingbin Yang*. Stachyose combined with tea polyphenols mitigated metabolic disorders in high fructose diet-fed mice as studied by GC-MS metabolomics approach. CyTA-Journal of Food, 2018, 16, 516-524 (SCI四区, IF 1.371)

  31. Xingyu Wang, Anning Gao, Yadong Jiao, Yan Zhao, Xingbin Yang*. Antitumor effect and molecular mechanism of antioxidant polysaccharides from Salvia miltiorrhiza Bunge in human colorectal carcinoma LoVo cells. International Journal of Biological Macromolecules, 2018, 108, 625-634 (SCI二区, IF 3.909)

  32. Xichuan Zhai, Dehui Lin*, Yan Zhao, Wenwen Li, Xingbin Yang*. Effects of dietary fiber supplementation on fatty acid metabolism and Intestinal microbiota diversity in C57BL/6J mice fed with a high-fat diet. Journal of Agricultural and Food Chemistry, 2018, 66, 12706-12718 (SCI一区, IF 3.412)

  33. Mengfan Jia, Zhong Zhang*, Jinhua Li, Xin Ma, Lingxin Chen, Xingbin Yang*. Molecular imprinting technology for microorganism analysis. Trends in Analytical Chemistry, 2018, 106, 190-201 (SCI二区, IF 7.030)

  34. Xichuan Zhai, Caiping Zhu*, Yun Li, Yang Zhang, Zhen Duan, Xingbin Yang*. Optimization for pectinase-assisted extraction of polysaccharides from pomegranate peel with chemical composition and antioxidant activity. International Journal of Biological Macromolecules, 2018, 109, 244-253 (SCI二区, IF 3.909)

  35. Xichuan Zhai, Caiping Zhu*, Yang Zhang, Jingru Sun, Aamina Alim, Xingbin Yang*. Chemical characteristics, antioxidant capacities and hepatoprotection of polysaccharides from pomegranate peel. Carbohydrate Polymers, 2018, 202, 461-469 (SCI二区, IF 5.158)

  36. Shuaishuai Yan, Hongjun Shao*, Zhihao Zhou, Qi Wang, Luhua Zhao, Xingbin Yang*. Non-extractable polyphenols of green tea and their antioxidant, anti-α-glucosidase capacity, and release during in vitro digestion. Journal of Functional Foods, 2018, 42, 129-136 (SCI二区, IF 3.470)

  37. Qi Wang, Junxia Cheng, Lixia Wang, Shuaishuai Yan, Ruiqin Wang, Haisheng Zhang, Hongjun Shao*, Xingbin Yang*. Valorization of spent shiitake substrate for recovery of antitumor fungal sterols by ultrasound-assisted extraction. Journal of Food Biochemistry, 2018, 42:e12602 (SCI 四区, IF 1.552)

  38. Yalong Lu, Wenfeng Li*, Xingbin Yang*. Soluble soybean polysaccharides enhance the protective effects of genistein against hepatic injury in high L-carnitine-fed mice. Food & Function, 2017, 8, 4364-4373 (SCI一区, IF 3.289)

  39. Daoyuan Ren, Jianrui Qi, Anqi Xie, Mengfan Jia, Xingbin Yang*, Hang Xiao*. Encapsulation in lysozyme/A. Sphaerocephala Krasch polysaccharide nanoparticles increases stability and bioefficacy of curcumin. Journal of Functional Foods, 2017, 38, 100-109 (SCI一区, IF 3.470)

  40. Yalong Lu, Yuanyuan Hu, Tong Wang, Xingbin Yang, Yan Zhao*. Rapid determination and quantitation of compositional carbohydrates to identify honey by capillary zone electrophoresis. CyTA-Journal of Food, 2017, 15(4), 531-537 (SCI, IF 1.371)

  41. Yalong Lu, Dehui Lin, Wenfeng Li, Xingbin Yang*. Non-digestible stachyose promotes bioavailability of genistein through inhibiting intestinal degradation and first-pass metabolism of genistein in mice. Food & Nutrition Research, 2017, 61, e1369343 (SCI二区, IF 2.086)

  42. Yalong Lu, Jinwen Chen, Daoyuan Ren, Xingbin Yang*, Yan Zhao*. Hepatoprotective effects of phloretin against CCl4-induced liver injury in mice. Food and Agricultural Immunology, 2017, 28(2), 211-222 (SCI二区, IF 2.568)

  43. Di Huang, Wenfeng Li*, Hongjun Shao, Anning Gao, Xingbin Yang*. Colour, texture, microstructure and nutrient retention of Kiwifruit slices subjected to combined air-impingement jet drying and freeze drying. International Journal of Food Engineering, 2017, 20160344 (SCI, IF 0.923)

  44. Mengfan Jia, Zhong Zhang*, Jinhua Li, Hongjun Shao, Lingxin Chen, Xingbin Yang*. A molecular imprinting fluorescence sensor based on quantum dots and a mesoporous structure for selective and sensitive detection of 2,4-dichlorophenoxyacetic acid. Sensors and Actuators B-Chemical, 2017, 252, 934-943 (SCI一区, IF 5.667)

  45. Dongyu Li, Zhao Li*, Weihua Chen, Xingbin Yang*. Imaging and detection of carboxylesterase in living cells and Zebrafish pretreated with pesticides by a new near-infrared fluorescence off-on probe. Journal of Agricultural and Food Chemistry, 2017, 65, 4209-4215 (SCI一区, IF 3.412)

  46. Xichuan Zhai, Daoyuan Ren*, Yiyang Luo, Yuanyuan Hu, Xingbin Yang*. Chemical characteristics of an Ilex Kuding tea polysaccharide and its protective effects against high fructose-induced liver injury and vascular endothelial dysfunction in mice. Food & Function, 2017, 8, 2536-2547 (SCI一区, IF 3.289)

  47. Daoyuan Ren, Dehui Lin*, Aamina Alim, Quan Zheng, Xingbin Yang*. Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells. Food & Function, 2017, 8, 1299-1312 (SCI一区, IF 3.289)

  48. Mengfan Jia, Daoyuan Ren,* Yan Nie, Xingbin Yang*. Beneficial effects of apple peel polyphenols on vascular endothelial dysfunction and liver injury in high choline-fed mice. Food & Function, 2017, 8, 1282-1292 (SCI一区, IF 3.289)

  49. Ting Li, Xinshan Lu, Xingbin Yang*. Evaluation of clinical safety and beneficial effects of stachyose-enriched α-galacto-oligosaccharides on gut microbiota and bowel function in humans. Food & Function, 2017, 8, 262-269 (SCI一区, IF 3.289)

  50. Zhihao Zhou, Hongjun Shao*, Xiao Han, Kaijie Wang, Cuiping Gong, Xingbin Yang*. The extraction efficiency enhancement of polyphenols from Ulmus pumila L. barks by trienzyme-assisted extraction. Industrial Crops and Products, 2017, 97, 401-408 (SCI一区, IF 3.849)

  51. Zuoxu Hou, Yuanyuan Hu, Xingbin Yang*, Wensheng Chen*. Antihypertensive effects of Tartary buckwheat flavonoids by improvement of vascular insulin sensitivity in spontaneously hypertensive rats. Food & Function, 2017, 8, 4217-4228 (SCI一区, IF 3.289)

  52. Xinwei Tian, Zhao Li*, Yaxing Pang, Dongyu Li, Xingbin Yang*. Benzoyl peroxide detection in real samples and Zebrafish imaging by a designed near-infrared fluorescent probe. Journal of Agricultural and Food Chemistry, 2017, 65, 9553-9558 (SCI一区, IF 3.412)